Empowering Science
Empowering Science
Empowering Science
The EpiFinder Platform
EpiFinder accelerates breakthroughs in biomedical research, drug discovery, and diagnostics through its ability to generate high-quality data at scale.
The EpiFinder Platform
EpiFinder accelerates breakthroughs in biomedical research, drug discovery, and diagnostics through its ability to generate high-quality data at scale.
Innovative Epigenetics Research
It provides researchers with the tools to explore new avenues in drug development and precision medicine by revealing critical epigenetic patterns.
Innovative Epigenetics Research
It provides researchers with the tools to explore new avenues in drug development and precision medicine by revealing critical epigenetic patterns.
The EpiFinder Platform
EpiFinder accelerates breakthroughs in biomedical research, drug discovery, and diagnostics through its ability to generate high-quality data at scale.
Innovative Epigenetics Research
It provides researchers with the tools to explore new avenues in drug development and precision medicine by revealing critical epigenetic patterns.
Blood-Based Epigenomics
This enables researchers to detect molecular biomarkers from blood samples, offering a non-invasive method for early disease detection and personalized treatments.
Blood-Based Epigenomics
This enables researchers to detect molecular biomarkers from blood samples, offering a non-invasive method for early disease detection and personalized treatments.
Blood-Based Epigenomics
This enables researchers to detect molecular biomarkers from blood samples, offering a non-invasive method for early disease detection and personalized treatments.
Comprehensive Product Portfolio
These commercial kits provide comprehensive solutions for researchers in fields like diagnostics, drug development, and personalized medicine.
Comprehensive Product Portfolio
These commercial kits provide comprehensive solutions for researchers in fields like diagnostics, drug development, and personalized medicine.
Scalable & Cost-Efficient Data
This efficiency drives faster research cycles and allows for expanded accessibility to high-quality epigenetic data.
Scalable & Cost-Efficient Data
This efficiency drives faster research cycles and allows for expanded accessibility to high-quality epigenetic data.
Comprehensive Product Portfolio
These commercial kits provide comprehensive solutions for researchers in fields like diagnostics, drug development, and personalized medicine.
Scalable & Cost-Efficient Data
This efficiency drives faster research cycles and allows for expanded accessibility to high-quality epigenetic data.
Features & Benefits
• Multiplex • High throughput • High-quality data • Quantitative read-out • Consistent, reproducible results • Simplified results • Easy-to-use • Low amounts of input material • Ability to combine studies of DNA methylation and histone modifications for a streamlined workflow • Validated antibodies • Optimized to work with an array of starting materials
Features & Benefits
• Multiplex • High throughput • High-quality data • Quantitative read-out • Consistent, reproducible results • Simplified results • Easy-to-use • Low amounts of input material • Ability to combine studies of DNA methylation and histone modifications for a streamlined workflow • Validated antibodies • Optimized to work with an array of starting materials
Features & Benefits
• Multiplex • High throughput • High-quality data • Quantitative read-out • Consistent, reproducible results • Simplified results • Easy-to-use • Low amounts of input material • Ability to combine studies of DNA methylation and histone modifications for a streamlined workflow • Validated antibodies • Optimized to work with an array of starting materials
quantitative ChIP-seq tracks
quantitative ChIP-seq tracks
quantitative ChIP-seq tracks
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A Revolutionary
Technology for Epigenetics
A Revolutionary
Technology for Epigenetics
We’ve added unparalleled high-throughput, multiplex, quantitative capabilities to traditional (ChIP-seq) combined these with proprietary LACODE adaptor design and barcoding technology to deliver a patented, first-in-class technology that enables researchers to streamline large-scale quantitative epigenomics experiments.
We’ve added unparalleled high-throughput, multiplex, quantitative capabilities to traditional (ChIP-seq) combined these with proprietary LACODE adaptor design and barcoding technology to deliver a patented, first-in-class technology that enables researchers to streamline large-scale quantitative epigenomics experiments.
How It Works
How It Works
How It Works
The Process
The Process
The Process
1. Fragment Chromotain
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1. Fragment Chromotain
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1. Fragment Chromotain
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2. Barcode Nucleosomes
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2. Barcode Nucleosomes
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2. Barcode Nucleosomes
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3. Immunoprecipitation
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3. Immunoprecipitation
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3. Immunoprecipitation
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4. Purify DNA
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4. Purify DNA
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4. Purify DNA
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5. Library Amplification
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5. Library Amplification
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5. Library Amplification
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6. Illumina Sequencing
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6. Illumina Sequencing
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6. Illumina Sequencing
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Open Source Pipeline
Open Source Pipeline
Open Source Pipeline
Next-Level, Quantitative Data
The EpiFinder™ platform yields exquisitely reproducible and quantitative data because samples are pooled early in the workflow. This removes the sample-to-sample variation typically seen in parallelized workflows, and allows quantitative comparisons across all samples. Chromatin fragments carrying the target epitope (e.g. hPTM) compete for the available antibody binding sites in each ChIP reaction, and the proportion of fragments captured in the ChIP reaction is directly proportional to the relative abundance of the hPTMs in each sample.
The EpiFinder™ platform yields exquisitely reproducible and quantitative data because samples are pooled early in the workflow. This removes the sample-to-sample variation typically seen in parallelized workflows, and allows quantitative comparisons across all samples. Chromatin fragments carrying the target epitope (e.g. hPTM) compete for the available antibody binding sites in each ChIP reaction, and the proportion of fragments captured in the ChIP reaction is directly proportional to the relative abundance of the hPTMs in each sample.
The EpiFinder™ platform yields exquisitely reproducible and quantitative data because samples are pooled early in the workflow. This removes the sample-to-sample variation typically seen in parallelized workflows, and allows quantitative comparisons across all samples. Chromatin fragments carrying the target epitope (e.g. hPTM) compete for the available antibody binding sites in each ChIP reaction, and the proportion of fragments captured in the ChIP reaction is directly proportional to the relative abundance of the hPTMs in each sample.
Custom Analysis Pipelines
Custom Analysis
Pipelines
Simple Sample-to-Result Workflow and Easy-to-Interpret Results; Epigenica’s open-source, custom-designed pipelines make it easy to process and analyze the vast quantitative data generated from the EpiFinder™ platform. The custom pipeline analysis performs all necessary demultiplexing, deduplication, genomic mapping, filtering, scaling steps to generate quantitative output tracks for easy visualization and downstream analysis, as well as a wealth of quality control (QC) indicators.
Simple Sample-to-Result Workflow and Easy-to-Interpret Results; Epigenica’s open-source, custom-designed pipelines make it easy to process and analyze the vast quantitative data generated from the EpiFinder™ platform. The custom pipeline analysis performs all necessary demultiplexing, deduplication, genomic mapping, filtering, scaling steps to generate quantitative output tracks for easy visualization and downstream analysis, as well as a wealth of quality control (QC) indicators.
Simple Sample-to-Result Workflow and Easy-to-Interpret Results; Epigenica’s open-source, custom-designed pipelines make it easy to process and analyze the vast quantitative data generated from the EpiFinder™ platform. The custom pipeline analysis performs all necessary demultiplexing, deduplication, genomic mapping, filtering, scaling steps to generate quantitative output tracks for easy visualization and downstream analysis, as well as a wealth of quality control (QC) indicators.